VfL Bochum won the 2020-21 2. Bundesliga with 67 points.
| # | Team | Pts | P | W | D | L | GF | GA | GD | Last 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  VfL Bochum | 67 | 34 | 21 | 4 | 9 | 66 | 39 | +27 | WLWDW |
| 2 |  SpVgg Greuther Fürth | 64 | 34 | 18 | 10 | 6 | 69 | 44 | +25 | LWDWW |
| 3 |  Holstein Kiel | 62 | 34 | 18 | 8 | 8 | 57 | 35 | +22 | WWWLL |
| 4 |  Hamburger SV | 58 | 34 |
| 16 |
| 10 |
| 8 |
| 71 |
| 44 |
| +27 |
| DDWLW |
| 5 |  Fortuna Dusseldorf | 56 | 34 | 16 | 8 | 10 | 55 | 46 | +9 | LWDWL |
| 6 |  Karlsruher SC | 52 | 34 | 14 | 10 | 10 | 51 | 44 | +7 | DLDWW |
| 7 |  SV Darmstadt 98 | 51 | 34 | 15 | 6 | 13 | 63 | 55 | +8 | WWWWW |
| 8 |  1. FC Heidenheim | 51 | 34 | 15 | 6 | 13 | 49 | 49 | 0 | LLWLL |
| 9 |  SC Paderborn 07 | 47 | 34 | 12 | 11 | 11 | 53 | 45 | +8 | DWWLD |
| 10 |  FC St. Pauli | 47 | 34 | 13 | 8 | 13 | 51 | 56 | -5 | LWLLL |
| 11 |  1. FC Nürnberg | 44 | 34 | 11 | 11 | 12 | 46 | 51 | -5 | WDLDW |
| 12 |  Erzgebirge AUE | 44 | 34 | 12 | 8 | 14 | 44 | 53 | -9 | WDLLW |
| 13 |  Hannover 96 | 42 | 34 | 12 | 6 | 16 | 53 | 51 | +2 | LLLWL |
| 14 |  Jahn Regensburg | 38 | 34 | 9 | 11 | 14 | 37 | 50 | -13 | DLLLW |
| 15 |  SV Sandhausen | 34 | 34 | 10 | 4 | 20 | 41 | 60 | -19 | LLLWL |
| 16 |  VfL Osnabrück | 33 | 34 | 9 | 6 | 19 | 35 | 58 | -23 | DLWWL |
| 17 |  Eintracht Braunschweig | 31 | 34 | 7 | 10 | 17 | 30 | 59 | -29 | LLDLL |
| 18 |  FC Wurzburger Kickers | 25 | 34 | 6 | 7 | 21 | 37 | 69 | -32 | LDLWD |