| # | Team | Pts | P | W | D | L | GF | GA | GD | Last 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 67 | 34 | 19 | 10 | 5 | 72 | 26 | +46 | WWDLW | |
| 2 | 65 | 34 | 20 | 5 | 9 | 63 | 50 | +13 | DWWWW | |
| 3 | 55 | 34 | 16 | 7 | 11 | 57 | 41 | +16 | DLWWW | |
| 4 | 53 | 34 | 15 | 8 | 11 | 50 | 41 | +9 | LWLLW | |
| 5 | 49 | 34 | 12 | 13 | 9 | 64 | 56 | +8 | WWDLW | |
| 6 | 48 | 34 | 14 | 6 | 14 | 47 | 56 | -9 | WWWWL | |
| 7 | 48 | 34 | 14 | 6 | 14 | 44 | 53 | -9 | LWLLW | |
| 8 | 46 | 34 | 10 | 16 | 8 | 46 | 41 | +5 | LDWDL | |
| 9 | 42 | 34 | 13 | 3 | 18 | 44 | 52 | -8 | WWWDL | |
| 10 | 42 | 34 | 10 | 12 | 12 | 47 | 50 | -3 | LLLWD | |
| 11 | 40 | 34 | 10 | 10 | 14 | 48 | 54 | -6 | WWDLL | |
| 12 | 39 | 34 | 10 | 9 | 15 | 39 | 48 | -9 | WLLWD | |
| 13 | 34 | 34 | 9 | 7 | 18 | 49 | 66 | -17 | LLLLL | |
| 14 | 27 | 34 | 7 | 6 | 21 | 36 | 71 | -35 | DLLLL |
| # | Team | Pts | P | W | D | L | GF | GA | GD | Last 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 67 | 34 | 21 | 4 | 9 | 66 | 38 | +28 | LDWWL | |
| 2 | 56 | 34 | 16 | 8 | 10 | 65 | 49 | +16 | LWDLD | |
| 3 | 53 | 34 | 14 | 11 | 9 | 48 | 37 | +11 | WWDLW | |
| 4 | 50 | 34 | 14 | 8 | 12 | 58 | 51 | +7 | LWWDW | |
| 5 | 50 | 34 | 13 | 11 | 10 | 52 | 41 | +11 | WDDLW | |
| 6 | 48 | 34 | 14 | 6 | 14 | 48 | 51 | -3 | LDLLW | |
| 7 | 47 | 34 | 12 | 11 | 11 | 43 | 45 | -2 | DLLDW | |
| 8 | 46 | 34 | 11 | 13 | 10 | 53 | 53 | 0 | WWDLL | |
| 9 | 43 | 34 | 12 | 7 | 15 | 40 | 57 | -17 | LWWWL | |
| 10 | 43 | 34 | 11 | 10 | 13 | 46 | 57 | -11 | WWLWD | |
| 11 | 41 | 34 | 12 | 5 | 17 | 47 | 46 | +1 | WLDLD | |
| 12 | 40 | 34 | 11 | 7 | 16 | 42 | 54 | -12 | DWWWL | |
| 13 | 36 | 34 | 10 | 6 | 18 | 43 | 56 | -13 | DWLWL | |
| 14 | 35 | 34 | 8 | 11 | 15 | 52 | 69 | -17 | LDLWD |
Los Angeles FC won the 2022 MLS title in the playoffs. Philadelphia Union finished top of the regular season with 67 points. 28 teams contest the competition.