| # | Team | Pts | P | W | D | L | GF | GA | GD | Last 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 66 | 34 | 20 | 6 | 8 | 57 | 35 | +22 | LWWWL | |
| 2 | 65 | 34 | 20 | 5 | 9 | 52 | 40 | +12 | WWDWW | |
| 3 | 65 | 34 | 19 | 8 | 7 | 81 | 55 | +26 | DLWWW | |
| 4 | 59 | 34 | 19 | 2 | 13 | 55 | 46 | +9 | WLLWW | |
| 5 | 56 | 34 | 17 | 5 | 12 | 50 | 44 | +6 | WLWLL | |
| 6 | 54 | 34 | 16 | 6 | 12 | 58 | 45 | +13 | LLWDL | |
| 7 | 54 | 34 | 14 | 12 | 8 | 55 | 51 | +4 | LDLDW | |
| 8 | 53 | 34 | 15 | 8 | 11 | 68 | 60 | +8 | WWWDD | |
| 9 | 53 | 34 | 14 | 11 | 9 | 63 | 51 | +12 | WDDLL | |
| 10 | 43 | 34 | 12 | 7 | 15 | 48 | 47 | +1 | LWLLL | |
| 11 | 36 | 34 | 9 | 9 | 16 | 44 | 51 | -7 | DLWLD | |
| 12 | 32 | 34 | 6 | 14 | 14 | 37 | 44 | -7 | DDDLW | |
| 13 | 28 | 34 | 6 | 10 | 18 | 34 | 60 | -26 | LLWDL | |
| 14 | 28 | 34 | 5 | 13 | 16 | 38 | 63 | -25 | DLLLD | |
| 15 | 26 | 34 | 5 | 11 | 18 | 30 | 66 | -36 | DLLLD |
| # | Team | Pts | P | W | D | L | GF | GA | GD | Last 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 63 | 34 | 19 | 6 | 9 | 64 | 41 | +23 | LDLWW | |
| 2 | 63 | 34 | 18 | 9 | 7 | 66 | 38 | +28 | DDWWL | |
| 3 | 60 | 34 | 17 | 9 | 8 | 65 | 40 | +25 | WWWLD | |
| 4 | 58 | 34 | 16 | 10 | 8 | 56 | 39 | +17 | WLDWL | |
| 5 | 55 | 34 | 15 | 10 | 9 | 58 | 48 | +10 | LDWWW | |
| 6 | 47 | 34 | 13 | 8 | 13 | 37 | 45 | -8 | WLLWL | |
| 7 | 44 | 34 | 11 | 11 | 12 | 52 | 55 | -3 | WDWLW | |
| 8 | 44 | 34 | 11 | 11 | 12 | 41 | 48 | -7 | LDDLL | |
| 9 | 41 | 34 | 12 | 5 | 17 | 38 | 49 | -11 | LWWLD | |
| 10 | 41 | 34 | 11 | 8 | 15 | 60 | 63 | -3 | LLWLW | |
| 11 | 41 | 34 | 11 | 8 | 15 | 44 | 56 | -12 | WLDLD | |
| 12 | 37 | 34 | 9 | 10 | 15 | 43 | 56 | -13 | LWLLD | |
| 13 | 32 | 34 | 8 | 8 | 18 | 44 | 58 | -14 | WWLWD | |
| 14 | 30 | 34 | 7 | 9 | 18 | 46 | 66 | -20 | LWLWW | |
| 15 | 28 | 34 | 7 | 7 | 20 | 46 | 70 | -24 | LLLLD |
Inter Miami won the 2025 MLS title in the playoffs. Philadelphia Union finished top of the regular season with 66 points. 30 teams contest the competition.